Gab2 Phosphorylation by RSK Inhibits Shp2 Recruitment and Cell Motility
نویسندگان
چکیده
منابع مشابه
Crucial roles of RSK in cell motility by catalysing serine phosphorylation of EphA2
Crosstalk between inflammatory signalling pathways and receptor tyrosine kinases has been revealed as an indicator of cancer malignant progression. In the present study, we focus on EphA2 receptor tyrosine kinase, which is overexpressed in many human cancers. It has been reported that ligand-independent phosphorylation of EphA2 at Ser-897 is induced by Akt. We show that inflammatory cytokines p...
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ژورنال
عنوان ژورنال: Molecular and Cellular Biology
سال: 2013
ISSN: 0270-7306
DOI: 10.1128/mcb.01353-12